Customized Medicines

Customized Medicines
Dr. Sonja O'Bryan, Pharm.D., ABAAHP Board Certified Health Practitioner Diplomate-American Academy of Anti-Aging Medicine: "Creative Medicines" for Hormones-Weight-Pain-Fatigue-Skin Diseases-Pediatrics-Autoimmune Disorders-Veterinary Needs. Using Complimentary, Integrative, Regenerative, Bio-Identical, and Lifestyle Medicine For Health and Healing.

Wednesday, July 5, 2017

Experience Is What You Need- Dr. Sonja's BIO

Sonja O’Bryan, received her Bachelor’s degree from St. Louis College of Pharmacy and her Doctorate from the University of Arkansas for Medical Sciences.  She is a Board Certified Healthcare Diplomate, with the American Academy of Anti-Aging Medicine and uses natural, complimentary, pharmaceutical, and integrative approaches in her expertise with patients and their personal needs.  Use natural when possible and pharmaceutical ONLY when necessary is a position statement that she follows in her approach to patient care. 

~(The American Board of Anti-Aging Health Practitioners was founded in 1999 to provide advanced education, representation, and specialty recognition of scientific and healthcare professionals. The A4M and ABAAHP represent over 26,000 physicians, scientific and healthcare practitioners from 120+ nations. The process involves a written examination, which demonstrates proficiency in several key areas of Anti-Aging medicine. Along with proved competency by examination, the candidate must also provide documentation of 150 hours over 8 years of applicable continuing education to the field of anti-aging medicine, medical licenses and obtained degrees, and curriculum vitae showing professional experiences in customized, integrative, complimentary, and regenerative clinical care. After passing the written exam and completion of certification criteria, a certificate is issued to the healthcare practitioner confirming their status as a Diplomate of Anti-Aging Medicine.)

Dr. Sonja O'Bryan has a broad range of experience including hospital administration, community pharmacy, long term care and geriatrics consulting, oncology care, and in academia as a University Professor and graduate student preceptor.  She has a tremendous passion to help people become healthy in all areas of their life and meshes the spiritual, physical, mental, and emotional sides of care in her approach to better living.  Dr. O'Bryan currently does a great deal of teaching to community, church, and medical groups across the U.S., and has collaborated with several major pharmaceutical companies as an Advisory Board member for medicines coming to the U.S. market.  She writes and publishes a blog that reaches across the world and has 100,00 hits on HOT topics that affect men and women as they go through the aging process. 




In her book, “Living Hormoniously: A Hormone Handbook for the Everyday Women”, Dr. O'Bryan exposes the real life issues of the day with stories of women going through the changes of “The Change.”  Every woman, no matter her stage of aging, can find useful information in her easy to read handbook.  She offers testing, evaluation, and treatment of hormonal, adrenal, and thyroid imbalance in helping women and men to look better, live better, and feel better.  For a private and personal consultation call 417-334-4032 (Lakeland Wellness inside Providence Medical Spa Branson MO) or email: drsonjaobryan@gmail.com






Dr. O’Bryan also consults with patients on customized therapies for a host of other conditions such as psoriasis and eczema, Alzheimer’s disease, wounds, fatigue, stress, pain, gastrointestinal issues (Crohn’s, IBS, diverticulitis), anxiety, depression, and conditions associated with cancer.  She works closely and directly with physicians, nurse practitioners, chiropractors, and naturopathic physicians using her knowledge and experiences of the past 27 years to formulate customized therapies for specific needs.  To her colleagues, she is known as a practical, ‘go-to’ resource with highly effective and customized options for health and healing.   ~Catch Dr. Sonja O’Bryan’s Facebook page to stay tuned to updates and information in the Anti-Aging and Hormonal Imbalance World under 'Sonja Pinnell O’Bryan'.



Personally, Dr. Sonja O’Bryan has been married to her husband Dean O’Bryan for 27 years and they have three incredible children, who help them in their numerous roles and responsibilities.  She will tell you that her family is the greatest joy in life.  Rev. Dean and Rev./Dr. Sonja are both licensed ministers with the Assemblies of God and can be found on weekends traveling and ministering in churches locally and across the United States in their position and role as Missionary Associates with  Convoy of Hope/Rural Compassion.  The O'Bryan's also own their own small businesses including the White River Coffee Co. in Rockaway Beach MO.  The coffee shop is a marketplace ministry site where locals, visitors, and mission team members can hang out and enjoy the wonderful gift of coffee and conversation. On any given day, the "O's" truly enjoy meeting the needs of others, whether at home, at the office, or on the field of ministry and missions.



To book Dr. Sonja for your next event, email drsonjaobryan@gmail.com.   Here’s just a few of the great titles  and teaching programs that can be customized for the interest of your audience and event.

~Weight Loss: The Skinny on Losing Fat

~Fierce, Female, and Fabulous: Women’s Health and Healing

~Extreme Hormone Makeover:  Hormones, Stress, and All the Hot Topic "Issues" of Aging

~The Impact of Stress on Your Health and Longevity and What YOU Can Do!

~Help! I'm a HOT Mess!!

Thursday, May 25, 2017

Are You A Hot Mess?

Aging is natural, if you live long enough to experience it!  We can all attest that as the birthdays come, so do other strange and unusual things.   Why is that happening?  Do I look as bad as I feel?  Did I just lose it? What's up with that?  These are common questions you might be asking yourself.    Various symptoms often accompany aging including loss of energy, weight gain, brain fog, irritability, achy/squeaky joints, insomnia, decreased libido, sluggish bowel function, bladder leaks, sensitivity to heat and cold, irregular menstrual cycles, restless sleep, afternoon fatigue, and so on.  But is it "normal" to have to deal with these things year after year, after year? For some sufferers, they just commit to the reality of the advancing biological clock and move on.  For others, they choose to fight and conquer what others think is "normal".  My opinion is that these symptoms are a sign of decline in biologically identical hormones.  It's like your body is suffering a drought.  I'm personally in the latter group and test my hormones EVERY year (without fail) to make sure things are ship-shape and keeping me at the best performance possible. I'm not suggesting that 40&50-somethings have the levels of a 20 year old, but getting reasonably near that mark is where most feel their best.  I can write that with a lot of confidence and experience because our team takes care of hundreds of men and women who are addressing their hormonal imbalances.   And, this area of healthcare is growing daily.   Please, look at the possibilities of aging (lists above and below) and check yourself before you wreck yourself trying to cope with the changes. 



All hormone therapy is not created equal and the best option, in my professional and personal opinion, is customized, bio-identical hormone replacement therapy.  That simply means it's a direct structural match to what the body produces on it's own and to what you as an individual are missing.  Give someone what's missing and in the dose appropriate to address their hormonal deficiencies, and they will live, look, and feel so much better.  Bio-identical Hormone Replacement Therapy (BHRT) simply replenishes what the hormonal drought has caused with the aging process.  Lifestyle, nutrition, and exercise also play a beneficial role in bringing everything together for a person who is struggling along in the aging process.

Here's an example of what hormonal shifts can do:
Estrogen Dominance (aka Progesterone Deficiency) is something that I commonly see in the patients that seek testing and evaluation of their hormones.  They may be common symptoms, but they are not to be considered normal for someone wanting to feel and look their best.  Here's a list of the effects from this type of natural hormonal shift in the body and what can happen to women of ANY age:

Premenstrual breast tenderness
Mood swings, irritability, and depression
Fluid retention and weight gain
Headaches, including migraines
Anxiety and panic attacks
Irregular menstrual cycles
Insomnia and restless sleep
Sagging skin and wrinkles
Dry eyes
Elevated blood pressure
Elevated cholesterol
Low thyroid function
Fatigue
Infertility
Loss of sexual desire
Bladder leaks with coughing, laughing, or sneezing
Uterine fibroids
Foggy thinking
Emotional sensitivity
Breast cancer
Joint aches
Sweats
Agitation

As something fun to celebrate all of my HOT MESS sisterhood out there, I had a T-shirt printed with my book title and logo Living Hormoniously on the back.  Little did I know that the shirts would make their way across the U.S.  It's fun to celebrate aging together with so many friends and family from the beautiful Midwest city of Branson MO.








If you are experiencing any of these, I would suggest you call our team.   A baseline test to evaluate and treat your hormones is key in feeling normal again.  Trust me, aging happens to everyone, but not everyone seeks professional help.  You have the most compelling of information right here, but you have to own it and address it. For a personal consultation email: thehormonemaven@gmail.com 


Wednesday, May 24, 2017

Tomorrow's Medicine TODAY! People Are Seeking Better Ways

The realm of integrative, complimentary, restorative, and anti-aging medicine is growing at an unprecedented rate.  It's exciting, because for years and years, myself and the team trudged along building a foundation for something that we knew would come.  Our team has been together for years now, which I love and I think is important. Yeah for us! Attending conferences, joining webinars, teaching programs to community groups and churches, going back to the classroom myself with the A4M, and talking to physicians was the norm for so long.  The time is here!!  Now, the calls are coming in to us with questions on how we might provide unique solutions to individuals needs.  I'm grateful for that and look forward to additional growth in the future.  It's coming!

There are things I've learned over the course of my professional career and some transitions that are taking place.   I encourage you to add you thoughts and comments about the view on "modern medicine".  Here's my two cents:

~People want NATURAL when possible. 

~People are seeking options that used to be considered "alternative".  Now we're finding that they should have been included all along.

~Hormonal imbalance affects everything from menstrual cycles, fertility, mood, vitality, heart health, bone strength, cognitive function, sexuality, rapid aging, weight management, sleep and the list could go on and on.  And except for menstrual cycles, that's a statement for both men and women.  We are seeing more and more attention being drawn to this in the media and in health articles.

~"Normal" ranges aren't always in sync with a patients symptoms.  For 30 years we had a "normal TSH range" for thyroid that has now been adjusted ~6 points lower.  That means that for decades, people were being told they were 'normal'.  They would be on therapy by today's tightened ranges.  Sad!  Medical oopsie that cannot be reversed.  We can't afford these kind of oo-boo's.   It really makes people wonder what the word "normal" really means, and if it can be trusted.

~Often nutraceuticals (vitamins, herbs, and supplements) can be used to treat/prevent common things.  If you are NOT on certain nutritionals (omega's, Vitamin D, core vitamins ), you are more prone to disease.  The studies prove it's true.

~Band-aid medicine is NOT the best answer.  It just covers up the problem.  What is the underlying reason?  That's what people want to know. 

~People can't afford to go to the doctor and are looking for other avenues and options to treat their problems or better yet, to prevent or minimize them from happening. I design custom regimens tailored to family disease and inherited risks.  If you are in your 20s, 30s, 40s, it's absolutely necessary for you to get started in prevention.  That's Anti-Aging medicine at it's best. If you are doing nothing, then take the next step and email: thehormonemaven@gmail.com

~ Customized medicine is often much less expensive than the pharmaceutical approach.  It's not just for the celebrities in Hollywood.   We have hundreds of women and men on Bio-identical Hormone Replacement Therapy and we've had some of them for many years.  Why is that?  They feel better and want to maintain their health and longevity as much as possible.

~Bio-identical Hormones are the best approach in treating imbalances and can change the "issues" men and women are having.  If you have never heard this term, please do some reading.  If you've never heard about Adrenal Fatigue, do some reading.  Please, please.

~Anti-depressants, Anti-anxiety medicines, pain medicines, and sleeping pills are prescribed as the magic cocktail for aging when other options need to be investigated.  Sadly, they have done a poor job at mitigating these conditions for the long haul.

~Diet and Lifestyle awareness is trending.  We all know we could do better.  Some choose to, some not so much, but overall I think there's an increased awareness.  (Maybe I'm just looking with a glass-half-full mentality??)

~Our modern day foods are saturated with pesticides, chemicals, preservatives, artificial sweeteners and hormones but the truly organic versions are way more expensive, so people can't afford to buy them.  Bringing those prices down is an economic benefit to healthcare costs in the end.  Reward farmers who want to provide quality and not quantity.  Reward consumers who want to eat better. Healthy should not only be for the wealthy.  Can I get an amen?

~People need more time with their doctor for their needs to be fully expressed.  The average time is about 7 minutes.  Sad! I hope you don't forget to remember (smile) what you're supposed to talk about in that short of a time period with your physician or practitioner.  Have you ever left the office saying, "Crud, I forgot to ask about that!"?  Of course you have.  When I wrote my hormone handbook, I included a section at the back of each chapter to allow personal notes as a reminder to discuss those issues with the doctor.  It has worked well for women. 

~We will see a growing number of physicians abandoning the corporate practice world to provide specialty care and to truly build relationships with their patients.  Its already happening and I can give you specific names.  High five to them!!

~There's something to this autism and ADHD  thing with children.  I don't have the answer, but I believe there's a need for funding in research and programs to evaluate every possible cause. (vaccines, food, maternity care, etc.). Integrative Medicine has done a great job in leading the way for possible reasons and interventions to help.  Parents of these children are heroes and sheroes!!

~People are starting to talk more openly and seek answers.  A referral is the highest compliment to me and I'm always thankful when a friend refers a friend.  Tell your story and your success and cheer each other on. 

~Statistics are now showing that half of Americans are headed for obesity.  That number is higher than ever.  There will be a tremendous burden to our healthcare system and to each of our pocket books if we don't turn this cat around.

~Pain management is a huge issue and prescription pain pills are known to cause problems with hormonal imbalance, gastrointestinal motility, respiratory function, and mental clarity.  We are providing a greater amount of customized pain therapies for those patients needing control of pain.  Physicians are now being educated about topical pain management more than ever before. 

~Customized therapy is not always a first thought with people.  But, you need to know it IS an option and the last thought should sometimes be your first thought.  Call us and we can offer options and bill your prescription insurance. 

~People are seeking physicians who are in tune with this niche of medicine.  The textbooks of 50 years ago are good, but we've come a long way baby and we now know so much more.  That's called progress and some providers just aren't willing to change. Thankfully, I work with some of the best and brightest this country has to offer and who take time to update their intellectual data bank.  They're out there, you just have to find them.

Okay, enough for today.  I would absolutely LOVE to hear your perspective on this note.  This is a compilation of what people are talking about in my world.  Comment away!



To your good health,
Dr. Sonja

Tuesday, May 23, 2017

Health and Technology Predictions: Will A Robot Provide Your Care?

Future Predictions for 2017-2045

Dr Robert Goldman, Co-Founder & Chairman-World Academy of Anti-Aging Medicine, weighs in with his latest set of predictions for health and technology.
It is estimated that the doubling time of medical knowledge in 1950 was 50 years; in 1980, 7 years; and in 2010, 3.5 years. In 2020 it is projected to be 0.2 years—just 73 days. Computer power is doubling every 18 months, so massive increases in scope and scale. Once nanotechnology and nano circuitry, stem cells, and genetic engineering, come on board, the world as we know it will be unrecognizable. Get ready for the first complete synthetic human brain, moon mining, chips implanted in our brains, self-driving cars, trucks and planes, robotic moon bases and maybe even high-speed rail linking London to Beijing.
The most popular movie super heroes demonstrate cellular regeneration like 'Wolverine' allowing mutations to enable rapid cellular repair & healing achieving Immortality, or Captain America in 1942 using Hormone Therapy/Steroid Augmentation to become an athletic Super Hero and with Cryonics/suspended animation freezing him into the 21st century. This Brave New World is coming into being faster than we imagined. To have the great jobs and careers of the future, you must embrace and see it before it arrives.
Radical Life Extension
Billions of dollars have recently flowed into Anti-Aging Medical research, from the likes of Silicon Valley & Biotech Startups chasing after the 'Fountain of Youth', such as Calico (Google), Johnson & Johnson, Human Longevity Inc, Elysium Health, Synthetic Genomics, GlaxoSmithKline / Sinclair, Startup Health, Mayo Clinic, Scripps Research, Roche , Novartis (Rapamycin), AstraZeneca, AbbVie, Pfizer, Sanofi, Medtronic/Covidien, IBM Watson Healthcare, Quest, Apple, Microsoft, Qualcomm, Facebook, Amazon, Novo Nordisk and other giants. They finally realize that Anti-Aging & Regenerative Medicine is the next generation of healthcare -the age of PRACTICAL IMMORTALITY, where lifespans of 120 to 150 in superior health may become commonplace and may be seen as early as 2029. Others such as Oracle co-founder Larry Ellison, for example, has given more than $430 million toward anti-aging research because he finds the quiet acquiescence of mortality “incomprehensible.” XPRIZE entrepreneur Peter H. Diamandis co-founded Human Longevity, which, in conjunction with StartUp Health, launched the Longevity Moonshot, whose mission is “to extend and enhance healthy life by 50+ years and change the face of aging.” Google co-founder Larry Page launched a biotech company called Calico, which aims to extend the human life span by a century. Calling it “a longer-term bet,” Page said he was confident they “can make good progress within reasonable timescales with the right goals and the right people.” PayPal co-founder Peter Thiel created Breakout Labs to fund scientists and start-ups that include some working on achieving immortality, and he invested millions in funding research to treat aging as an engineering problem to be solved at the cellular level by reprogramming cells to stop aging. The anti-aging literature is loaded with technologies to prolong lifespan by 20-40%, at least in lab animals. Interventions such as caloric restriction, rapamycin, stem cells, genetic engineering, nanotechnology and metformin, etc have been studied for decades for their anti-aging capacity. In the past several years, multiple scientific teams demonstrated the rejuvenating powers of young blood. A study published in the esteemed journal Nature found that eliminating senescent cells in aged mice boosted their lifespan by a hefty 30%. Hundreds of anti-aging drugs are now in the pipeline and billions of dollars are being expended to find real answers. The FDA finally recognized 'Aging' as a disorder that the medical community could target and potentially treat, something the American Academy of Ant-Aging Medicine (A4M) (www.Worldhealth.net, www.A4M.com) has been stating for decades. Notes A4M President Dr Ronald Klatz, "'Aging is Not Inevitable' and we are seeing the largest paradigm shift in the history of medicine." We know that lifespan has essentially been going up roughly 1 year in every 4, but healthspan is not going up at anywhere near the same rate. The United States spends 19% GDP on healthcare, most of which is used in the last 6 months of a person’s life. If you want an exciting career, the anti-aging & regenerative medicine marketplace is one to look at seriously. We can no longer practice the 'disease based' medicine of the past...preventative anti-aging & regenerative medicine is the only viable solution to prevent bankrupting of the national budgets due to massive chronic healthcare costs.
The Robots are Coming
Robotics is a rapidly emerging technology which will penetrate every aspect of business and our daily lives. This will replace massive numbers of manufacturing jobs and manual labor. Japan is expecting one in three of its population to be over the age of 65 by 2030, and one in five to be over 75, creating a major requirement for the care of the elderly. Japan is now using robots to service the elderly. A hotel opened in Japan in 2015 with lifelike robots, called 'Actroids', serving as the check-in staff. Aid assistance in nursing facilities is on the horizon, meaning many of the entry-level jobs in those areas will become obsolete just like bank tellers. Look at the field of Robotics, AI (Artificial Intelligence) and VR (Virtual Reality) technologies for massive growth industries.
Coastal Changes
Climate change will have a strong economic impact in the future. It is anticipated that by 2050, more than 40% of the world’s population will live under severe water stress, resulting in floods or drought that, combined, can put the economic value of assets at risk to record highs. Becoming efficient with resources is socially responsible and cost beneficial. Organizations need to adapt to increasing regulations controlling energy efficiency, waste, water leakage, urban congestion, transportation efficiency, land degradation, freight impact, and other factors. Allowing employees to work virtually also reduces the need for facilities and helps organizations minimize their carbon footprints.
New Energy Sources
Where we get our energy from will change dramatically. The U.S. military has pledged to get half its energy from renewable resources by 2020, and the Navy whole-heartedly believes it can turn to 50 percent biofuels by then. It makes political sense not to rely on volatile regions for energy, and this push could mean both cleaner vehicle fleets and a major bump in the competitiveness of biofuels in the market. The strangle hold that Middle Eastern oil holds will soon be an ancient memory. Biofuels and renewable clean energy are growth industries of the future..Oil and coal are on their way out.
3D Print Your Organs and Meat
3D Printable Organs are already in process via 3D “bioprint” organ tissues, a process that involves depositing a “bio-ink” made of cells precisely in layers, resulting in a functional living human tissue for use in the lab. These tissues should be better predictors of drug function than animal models in many cases. In the long-term, this has the potential to pave the way to “printing” human organs, such as kidneys, livers and hearts. By 2020, the goal is to have the technology be broadly used by pharmaceutical companies, resulting in the identification of safer and better drug candidates and fewer failures in clinical trials. ...This same 3D Printed technology via stem cells, is also being applied to meat production for human consumption. (Keith Murphy, CEO of Organovo -World Economic Forum)
World Will Get Very Small
There is major globalization shift in where business is conducted and is occurring now. McKinsey estimates that half of the world’s largest companies will be headquartered in what are now emerging markets, such as Brazil, India, and eastern European countries. Pressure from global competition and other factors resulted in over 40% of the companies that were in the Fortune 500 in 2000 falling off the list in the next several years. These were replaced largely by new global entrants and technology companies. This will continue to shift to farther parts of the planet.
The Job Skills/Info Gap
The Job Skills Gap and information Gap is the problem and not that workers are unskilled; it’s that workers don’t know what skills employers need. Technology is already disrupting existing jobs, and creating new jobs that never existed before. In fact, the top 10 in-demand jobs in 2010 did not even exist in 2004. Change is happening so rapidly that 65 percent of today’s grade school kids in the U.S. will end up at jobs that haven’t even been invented yet. If u wish to be competitive you must enhance your tech skill levels for future industries not yet mainstream. (Alexis Ringwald, Cofounder and CEO, LearnUp, -World Economic Forum)
Water as a Major Asset
Water is an asset not a liability. Driven by global population growth and rising water scarcity, the UN reports that 75 percent of the world’s available freshwater is already polluted. Under-investment in water management is exacerbating the problem, causing serious impacts on human health and the environment. A key challenge is the high capital cost, and high energy requirements, of current wastewater treatment and management systems. Desalination plants will spring up worldwide to create massive needed fresh water from sea ocean water. The ability to use biotechnology to extract resources, such as energy, from waste, and the dropping cost of industrial automation, will begin to change our approach to managing water globally. Rather than a liability, wastewater will be viewed as an environmental resource, providing energy and clean water to communities and industry, and ushering in a truly sustainable and economical approach to managing our water resources. (Matthew Silver, CEO of Cambrian Innovation-World Economic Forum)
Super Computers Replacing Your Doctor?
Supercomputers with artificial intelligence taking better care of you than your Doctor? IBM Watson has partnered with Celgene to better track negative drug side effects and IBM is applying its cognitive computing AI technology to recommend cancer treatment in rural areas in the U.S., India, and China. For example, IBM Watson could read a patient's electronic medical records, analyze imagery of the cancer, and even look at gene sequencing of the tumor to figure out the optimal treatment plan for a particular person. The IBM Watson programs are able to instantly scan the world's medical literature data for making a diagnosis and treatment plan, so in the future a nurse or tech may be able do a more detailed evaluation than even team of doctors. And coupled with advanced MRI, CT and PET scans, view the inner body in mind boggling ways and even treating cancers and other issues at the microscopic level. This will turn the medical profession on its ear. (Fortune Magazine)
The Nanobots are Coming
Nanobots (miniaturized robots as small as an atom or electron) could become commonplace and in the future, may even integrate with our brain matter allowing us to merge with computers and the 'Cloud' for a 'Singularity' or merging of our minds with machines & computers. Nanotechnology ("nanotech") is manipulation of matter on an atomic, molecular, and supramolecular scale. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology which is the manipulation of matter with at least one dimension sized from 1 to 100 nanometers and such technologies deal with the special properties of matter which occur below the given size threshold potential applications (including industrial and military). Governments have invested billions of dollars in nanotechnology research and can be as diverse as surface science, organic chemistry, molecular biology, semiconductor physics, microfabrication, molecular engineering, etc. The associated research and applications are equally diverse, ranging from extensions of conventional device physics to completely new approaches based upon molecular self-assembly, from developing new materials with dimensions on the nanoscale, to direct control of matter on the atomic scale. Nanotechnology may be able to create many new materials and devices with a vast range of applications, such as in nanomedicine, nanoelectronics, biomaterialsenergy production, and consumer products. On the other hand, nanotechnology raises many of the same issues as any new technology, including concerns about the toxicity and environmental impact of nanomaterials, and their potential effects on global economics, as well as speculation about various doomsday scenarios. These concerns have led to a debate among advocacy groups and governments on whether special regulation of nanotechnology is warranted..
So with nano circuitry, we may be able to live, basically, in a virtual world — Matrix style....and perhaps even Reincarnate deceased ones virtually and be able to "bring back" those lost through artificial intelligence states some scientists. By the 2030s perhaps we send nanobots into people's brains to extract memories of loved ones. Augment that with a DNA sampling of the deceased, and it may be possible to create a convincing virtual version of somebody who's passed on. This progress is so profound, that within 30 years, computational power of artificial intelligence will be a billion times that of human intelligence, allowing us to upload our minds and maybe even our very souls to a computer, leading to a form of connective 'Singularity', a term created by Google scientist Ray Kurzweil. Even Stephen Hawking thinks it's possible; "I think the brain is like a program in the mind, which is like a computer, so it's theoretically possible to copy the brain on to a computer and so provide a form of life after death," the physicist said. This may in fact lead to virtual bodies like the wild video games and Virtual Reality (VR) and Artificial Intelligence (AI) devices we seeing exploding on the scene: (PopSci.com)
Self-Driving Trucks and Cars
The push for self-driving cars is not just because motorists would rather let the machine do the work. It’s because taking humans out of equation could mean safer travel and smarter traffic flow. To look forward to how we will drive in 2020 you just have to look back to 1957. The US electricity industry ran a newspaper ad promising a life of leisure in the future with a now iconic image showing a near empty highway and a family in a self-driving car with a glass bubble roof. Instead of worrying about the road ahead, the family are doing what all families do in their downtime apparently — they play dominoes and clearly don’t have a care for skin cancer. When it comes to self-driving cars, the year 2020 doesn’t just mark a vision of the future but a deadline. Nissan and Mercedes-Benz have set 2020 down as when they plan to introduce cars that can navigate city streets without the need for a driver. Volvo, which will soon begin trialling self-driving cars in Australia, has taken that one step further. Back in 2008, Volvo’s lead safety expert Anders Eugensson predicted that “by 2020, nobody shall be seriously injured or killed in a new Volvo”. Since then, Volvo has added some fine print to that bold prediction. Volvo safety expert Trevor Rourke admitted earlier this year that “not even the Pope is infallible” but said the trend was towards zero fatalities by 2020. No matter how attentive a human driver can be, a self-automated car with lasers, radar, sonar and video sensors gives the car the edge in keeping an eye on the road. In many ways Google is leading the charge towards self-driving cars with its autonomous vehicles now having driving nearly 3 million self-autonomous kilometres with only a handful of minor accidents and most of them caused by drivers running into the self-driving car because they are distracted by the Google logo and sensors on the top. But other new players working on autonomous cars include Uber, Tesla and, if the rumours are true, Apple. As Telstra Chief Technology Officer Vish Nandlall says, we’re already down.
Driverless Trucks
Driverless trucks will be safer and cheaper than their human-controlled counterparts, but that doesn’t mean America’s 3.5 million professional truck drivers are giving up to the machines without a fight. Across the US, truckers collectively haul more than 10 Billion tons of freight each year, but it’s a tough job – the hours are long and lonely, the pay is low and the lifestyle is sedentary. In many ways it’s a job ripe for disruption; robots v truckers. “Picture the taxi drivers around the world acting in response to Uber,” says Andy Stern, the former former president of the Service Employees International Union, referring to protests and violence that erupted in many cities as the $62.5 Billion Silicon Valley on-demand ride-hailing firm challenged conventional, regulated taxis. “Truck drivers will follow a similar pattern,” says Stern. “There will be disruption in different places. You can imagine people ringing state capitals with their trucks.” Much has been written about the advent of the driverless car, with rival versions being developed by Google, Uber and Tesla, yet driverless trucks are likely to roll out at scale much sooner. “Individuals can make their own choices about whether they want to get into a driverless car or taxi, but labour-saving technology will be deployed by businesses much quicker,” explains Stern, whose book Raising the Floor explores the need for a universal basic income as technology replaces jobs. Mining giant Rio Tinto already uses 45 240-ton driverless trucks to move iron ore in two Australian mines, saying it is cheaper and safer than using human drivers. Now the race is on to put driverless trucks on public roads. In May 2015, the first self-driving truck hit the American road in the state of Nevada, and there have been several tests around the world since then including a convoy that drove across Europe to the port of Rotterdam. That convoy used a new automated driving technology called platooning, which connects trucks using Wi-Fi, sensors, GPS and cameras. The leading vehicle dictates speed and direction, while the rest automatically steer, speed up and slow down in close convoy. In San Francisco, former Googlers have launched a startup called Otto, which promises to retrofit vehicles with driverless capabilities for just $30,000. The average trucker’s wage is around $40,000 per year.
The potential saving to the freight transportation industry is estimated to be $168 Billion annually. The savings are expected to come from labor ($70 Billion), fuel efficiency ($35 Billion), productivity ($27 Billion) and accidents ($36 Billion), before including any estimates from non-truck freight modes like air and rail. It’s regulation, and not technology that stands in the way of eliminating people from behind the wheel. Although trucking companies are likely to lobby hard for the legal reform so they can save on labor, which represents an estimated 34% of operational costs per mile, Morgan Stanley conservatively estimates that the freight industry could save as $168 Billion annually by harnessing autonomous technology – $70 Billion of which would come from reducing staff. In addition to cost savings, fleets of automatedtrucks could save lives. Crashes involving large trucks killed 3,903 people in the US in 2014, according to the National Highway Traffic Safety Administration, and a further 110,000 people were injured. More than 90% of the accidents were caused at least in part by driver error. What next for drivers? Where does this leave the 3.5 million truckers whose livelihoods depend on the need for a human behind the wheel? Truck Driver is not a profession for the future.
Internet of Things
It’s the simplest of terms that is obsessing the tech industry and confusing the public: The 'Internet of Things'. There are currently 13.4 billion things connected in the world — smartphones, smart TVs, computers, tablets and the odd fridge and robotic vacuum. Juniper Research predicts that figure will reach 38.5 billion by 2020. Technology analysts Telsyte predict the number of connected devices in the average Australian home will jump from the current figure of nine to at least 24 and the internet-enabled white good will become the norm, just as smart TVs are now standard. This is another career growth area in the tech fields.
So we either prepare for these future high tech/Info tidal waves and embrace them, or be swept away by them.
Robert M. Goldman MD, PhD, DO, FAASP
Co-Founder & Chairman-World Academy of Anti-Aging Medicine
World Chairman-International Medical Commission
Co-Founder & Chairman of the Board-A4M
Founder & Chairman-International Sports Hall of Fame
President Emeritus-National Academy of Sports Medicine (NASM)
Chairman-U.S. Sports Academy’s Board of Visitors

Monday, January 9, 2017

Birth Control Pills and Depression. Is there a connection?

The ZRT Laboratory Blog

Posted by Margaret Groves on Saturday, 08 October 2016

Hormonal Contraceptives – Do They Increase Risk of Depression

shutterstock_174191402-998x666-423910-edited.jpgThere have been some articles going around the medical news reporting on a new Danish study  suggesting that hormonal contraception might increase risk of depression, and that previous studies may not have highlighted this link because they did not include women who stopped taking their birth control as a result of depressive symptoms. This study got around that problem by including in their survey women who had been using birth control at any time during the previous 6 months. So what is the fuss all about?

Findings from the study

The study did find an association between use of hormonal contraception and the subsequent use of antidepressant medications and diagnosis of depression. The risk of depression with contraceptive use decreased with increasing age, and was highest in the youngest age group studied, namely teenagers aged 15-19, than in the women aged 20-34. The authors acknowledged that antidepressants are prescribed for other reasons than depression. They also acknowledged that adolescent girls are “more vulnerable to risk factors for depression” than older women, partly explaining the higher incidence of antidepressant use in this age group.

Progestins versus progesterone

The study showed that progestin-only contraceptive products were the most likely to result in use of antidepressant medication or a diagnosis of depression. But an unfortunate confusion between progesterone and progestins was created by a statement in the introduction of the study  saying “The 2 female sex hormones – estrogen and progesterone – have been hypothesized to play a role in the cause of depressive symptoms.” This led to a claim in a popular article about this study that the authors theorized that progesterone, as well as the synthetic progestins used in hormonal contraceptives, plays a role in the development of depression.
A recent blog by ZRT’s senior research scientist and neurotransmitter expert Kate Placzek, PhD, has discussed the neuroendocrine functions of endogenous estrogen and progesterone. Briefly, sex hormones have neuromodulatory roles in brain development and neuronal plasticity, and the regulation of cognition, learning, memory, emotion, mood, and motor control. It’s understandable that mood varies at different times during the menstrual cycle as hormone levels shift dramatically and these neuromodulatory effects come into play. The blog also explains how depression can be a factor in some women, but not others, using hormonal contraception.

It’s important to understand that the study did not report the increased likelihood of using antidepressants as percentage increases, but rather in terms of a calculation of relative risk.

The study authors’ statement regarding estrogen and progesterone’s role in causing depressive symptoms cites 5 studies; however, 2 of these are only about estrogen’s effects, and 2 refer only to synthetic progestins used in oral contraceptives (not progesterone itself). The 5th was a study of experimental estrogen or progesterone replacement in a very small group of 10 women with premenstrual syndrome and 15 normal women. This study was designed only to study adverse mood symptoms in susceptible women who were prone to PMS. In the experiment, the women were first treated with leuprolide to completely suppress ovarian hormone production, and then the investigators looked at whether or not PMS symptoms returned when estrogen or progesterone was then replaced. Although they found an increase in sadness (not depression) in the women with PMS after this hormone replacement, no such increase was seen in the normal women – thus progesterone adversely affected mood only in those women who were prone to PMS. Also, since the PMS symptoms actually abated during the last week of the experimental hormone replacement, the authors stated that they couldn’t predict whether long-term or low-dose hormone treatment would result in adverse mood symptoms in women.
Adding to the confusion, another statement in the Danish study says “The addition of progesterone to hormone therapy has been shown to induce adverse mood effects in women”; yet this is referenced by 2 citations, both of which concerned a synthetic progestin, not natural progesterone.
The authors do, however, reference a review suggesting that neuroactive metabolites of progesterone, allopregnanolone and pregnanolone, can have adverse mood effects in some women as a result of modulatory effects on the GABA-A receptor, and that this can explain the effects of luteal phase levels of progesterone in women who suffer from PMS, who are particularly sensitive to such effects. This allopregnanolone paradox, known as such because it is found in some women but not the majority, was described in detail in a recent blog on PMS by Dr. Placzek.

How great is the risk of depression in hormonal contraceptive users?

At first glance, the figures seem very stark. An article on this study reported that the highest risk group, which consisted of teenage girls aged 15-19, were “80% more likely to be prescribed an antidepressant when they were on combined birth control pills and 120% more likely when they were on progestin-only pills.” However, it’s important to understand that the study itself did not report the increased likelihood of using antidepressants as percentage increases, but rather in terms of a calculation of relative risk. There is a baseline level of antidepressant use regardless of hormonal contraceptive use, and this is given a relative risk of 1.0. The teenage users of combined oral contraceptives had a calculated relative risk of 1.8, and the progestin-only pill users had a calculated risk of 2.2 compared to non-users. While these figures do represent the percentage increases in relative risk stated in the article, the statistics require more careful interpretation.
The authors also found that relative risk of depression peaked after 6 months of hormonal contraceptive use, and dropped off to a lower risk than non-users after 4 years of use. For people susceptible to such effects with hormonal contraceptives, symptoms would therefore appear relatively soon after starting use, giving the opportunity to switch to a different preparation or method of contraception.

Conclusion

This is an important study to add to others in the literature that have looked at depression associated with use of hormonal contraceptives, and a risk of depression, especially in teenagers, is certainly of concern. However, hormonal methods are overwhelmingly very safe and effective, and practitioners should weigh the pros and cons of each method of contraception when advising patients. Some women may be susceptible to adverse effects on mood, while others may not. The pros and cons of an unwanted pregnancy must also be weighed against any potential drawbacks to using an effective means of contraception.

Tuesday, November 1, 2016

The #1 Contributor to Better Health and Wellness

Oh my.....this is an article of a different kind.

I've had this topic on my mind for some time now and finally found the time to sit down and gather some thoughts and clinical evidence to help people in realizing what the BIGgest contributor to better health and wellness is.  In any given day, I respond to countless questions and sit down in private consultations reviewing health histories, lab values, family diseases, medications, supplements, and the like.  However, as I work with an individual, I'm always keenly in tune to something that is more important than any custom therapy or regimen that I could design for them.  It's not something that I create and dispense in a bottle, but it far surpasses anything on the pharmacy shelves when it comes to overall health, sense of wellness, and success in achieving a goal.  So what is it?  (I'm glad you asked)

Actually the question is not, "what is it?"but instead, "who is it?"  Humans are complex social creatures often defined by family, language, culture, nationality, religion, race, or perhaps even trade.  We are born into some of these groups, but we can choose to join others. Did you know that our PURPOSE is very much intertwined with the people we interact with (or perhaps those we choose not to interact with)? Scientific study results show that a higher level of purpose in life, through our personal associations, is associated with better health, increased participation and productivity, better socioeconomic status, and better outcomes for persons with addiction.  Even patients with Alzheimers were reported to have better cognitive function, despite their disease, when surrounded by positive people and purpose. In other words, your social network could be thrusting you forward, or pulling you down.  Now hold on, I'm not suggesting that you dump all of your friends, but I am suggesting that you pay attention to those that make you feel joy, strength, positive, at ease, and purposeful about life.  This important health contributor alone can make or break you. Literally!

Now let me touch on some specific details and evidence....

Weight Loss Success
When it comes to weight loss coaching, I'm very strategic to cover social networks with an individual.  In a published study of over 12,000 people followed for over 30 years, here's what the results showed. "A person's chances of becoming obese increased by 57% (95% confidence interval [CI], 6 to 123) if he or she had a friend who became obese in a given interval. Among pairs of adult siblings, if one sibling became obese, the chance that the other would become obese increased by 40% (95% CI, 21 to 60). If one spouse became obese, the likelihood that the other spouse would become obese increased by 37% (95% CI, 7 to 73)"  The bottom line is that, those people in your social network can propel you to your weight loss goal, or they can inhibit you in your success.  If you want to be successful at weight loss, make sure you have your family and friends on board with you. We all know it's a real drag to watch the family eating pizza and sugar donuts while we're up to our greens in leaf lettuce. So not fair right?

Family Dynamics 
 Basic family dynamics can have an overall impact on health.  It has been known for many years that marriage increases life expectancy, especially in men. Family stability also helps adolescents avoid poor lifestyle decisions and children in a stable and loving home have a better chance at doing well in their life goals.  I've always followed and parented by the standard that "our children only have ONE chance at a happy childhood." If they feel engaged, loved, and a sense of belonging to that family unit, they will do "life" much better. The family circle of influence can be very healthy, or very unhealthy.

Religious services
There's evidence supporting longer life expectancy in those that regularly attend religious services compared to those who rarely or never do. According to data published in 1999 this can translate into a seven-year difference in life expectancy.  This does not mean that private spirituality is not beneficial, but that social group gathering and interaction with others is healthy all the more.  Faith and purpose go hand in hand.  It's healthy!


Your team
If you are a professional, a leader, or in business here's a big secret to success and 'purpose' in what you are doing.  Make sure to line up the "who" before you chase the "what". In the book Good to Great, Jim Collin's leading point is that you need the right people on the bus before you decide where to take the bus.  People are not your greatest asset.  The RIGHT people (your team) are your greatest asset! Real success takes more than just YOU to get where you want to go.  Everyone can feel purpose when you're all on the same page and working towards a common goal.  It's healthy!

All-IN
You can ask those in 'my circle' about this personal attribute deep inside me.  If I'm in, I'm All-IN.  I choose my social network very carefully these days (disclaimer...it wasn't always that way).  There's nothing so healthy as being surrounded by personal connections or a 'community' where everyone is genuinely concerned about the group's health, but even more importantly, concerned about each of the individuals that make up the group.  If you feel consistently drained by a certain someone(s) inside a circle of influence, then maybe it's time to step back and evaluate the impact on you, your health, and your goals to achieve success.  It's healthy to do so!



This is not my typical blog on hormones, supplements, testing, etc. but it is so, so, so important to overall health.  If you are working at your best in the physiological areas and missing the link in social and emotional areas, then you're going to be sub-optimal in your quest to achieve better health.  Evaluate your purpose today and figure out what,  I mean who, is in the benefit column and who is in the deduction column.  Hopefully the positives will far outweigh the negatives.


All the best,

Dr. Sonja